Jeans for Genes: helping children with genetic disorders

Raised to date

£30,000,000

Research into a variety of genetic disorders, Great Ormond Street Hospital Charity

Great Ormond Street Hospital is home to the widest range of paediatric expertise in Britain.  It’s also the largest centre for research into childhood illness outside the United States.

A researcher at the Institute of Child Health A researcher at the ICH Photo: James Robertson

The money that you help us to raise on Jeans for Genes Day funds research at the hospital’s paediatric research centre, the UCL Institute of Child Health. 

Amongst the projects we're currently funding are:

  • The use of gene therapy in treating cystic fibrosis.  Researchers are looking at ways of inserting a healthy copy of the defective gene into lung cells to make them behave normally.
  • Whether 'immunotherapy' can be used in the treatment of a cancer called Ewing sarcoma.  This treatment modifies the body's own immune system to recognise cancer cells as 'foreign' and attack them.
  • Novel heart valve treatments for children with genetic cardiac disorders.  Researchers at the Institute are developing new ways to treat heart defects through a vein in a child's heart which has far fewer risks than open heart surgery.

There is much more research that the money you raise will help to support.  This is incredibly expensive so please register for a fundraising pack today.